| Pair Name | Resveratrol, Flutamide | ||
| Phytochemical Name | Resveratrol (PubChem CID: 445154 ) | ||
| Anticancer drug Name | Flutamide (PubChem CID: 3397 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Resveratrol, Flutamide | |||
| Disease Info | [ICD-11: 2C82.0] | Prostate cancer | Investigative | |
| Gene Regulation | Down-regulation | Expression | AR | hsa367 |
| In Vitro Model | LNCaP | Prostate carcinoma | Homo sapiens (Human) | CVCL_0395 |
| PC-3 | Prostate carcinoma | Homo sapiens (Human) | CVCL_0035 | |
| DU145 | Prostate carcinoma | Homo sapiens (Human) | CVCL_0105 | |
| Result | Resveratrol works in concert with antiandrogen flutamide to reduce the amount and activity of AR, suggesting new therapeutic strategies for the treatment of PCa. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Combination of resveratrol and antiandrogen flutamide has synergistic effect on androgen receptor inhibition in prostate cancer cells. Anticancer Res. 2011;31(10):3323-3330. | Click |
